Meanwhile, Nadal will be making his return to Grand Slam competition for the first time since a shock loss to Djokovic himself at Roland Garros.
The 13-time champion looked set to win his 14th title on the clay in Paris when the Serb defeated him in four sets in the semi-final.
The Spaniard has since revealed that a foot injury left him unable to play tennis for 20 days after, and he subsequently pulled out of Wimbledon and the Olympics.
Nadal has won the title in Flushing Meadows four times, more than Djokovic’s three despite the world number one favouring the hard court surface.
